Role of POLE and POLD1 in familial cancer | Genetics in Medicine
Ultra‐mutated colorectal cancer patients with POLE driver mutations exhibit distinct clinical patterns - Hu - 2021 - Cancer Medicine - Wiley Online Library
The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes: Cell
Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers | Journal for ImmunoTherapy of Cancer
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer | PLOS Genetics
Mutations in POLE and survival of colorectal cancer patients – link to disease stage and treatment - Stenzinger - 2014 - Cancer Medicine - Wiley Online Library
Cancers | Free Full-Text | Immune-Checkpoint Inhibitors (ICIs) in Metastatic Colorectal Cancer (mCRC) Patients beyond Microsatellite Instability
Comparative mutational analysis of distal colon cancer with rectal cancer
Purpose
Cancers | Free Full-Text | Biomarkers of Response and Resistance to Immunotherapy in Microsatellite Stable Colorectal Cancer: Toward a New Personalized Medicine
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair | eLife
Pathogenic, somatic POLE mutations in precursors of endometrial and... | Download Scientific Diagram
Somatic POLE exonuclease domain mutations elicit enhanced intratumoral immune responses in stage II colorectal cancer | Journal for ImmunoTherapy of Cancer
POLE signature mutations in colorectal cancer driver genes.... | Download Scientific Diagram
Mutational landscape of our colorectal cancer cohort. Tumors are... | Download Scientific Diagram
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer | PLOS Genetics
ESMO Virtual Congress 2020: High Activity of Nivolumab in Patients with Pathogenic Exonucleasic Domain POLE (edPOLE) Mutated Mismatch Repair Proficient Advanced Tumours
Colorectal cancer - Wikipedia
Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population | Scientific Reports
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer | bioRxiv
Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability | PLOS ONE
High mutational burden in colorectal carcinomas with monoallelic POLE mutations: absence of allelic loss and gene promoter methylation | Modern Pathology
